A Highly Intensified ART Regimen Induces Long-Term Viral Suppression and Restriction of the Viral Reservoir in a Simian AIDS Model

Stably suppressed viremia during ART is essential for establishing reliable simian models for HIV/AIDS. We tested the efficacy of a multidrug ART (highly intensified ART) in a wide range of viremic conditions (10(3)–10(7) viral RNA copies/mL) in SIVmac251-infected rhesus macaques, and its impact on...

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Detalhes bibliográficos
Main Authors: Shytaj, Iart Luca, Norelli, Sandro, Chirullo, Barbara, Della Corte, Alessandro, Collins, Matt, Yalley-Ogunro, Jake, Greenhouse, Jack, Iraci, Nunzio, Acosta, Edward P., Barreca, Maria Letizia, Lewis, Mark G., Savarino, Andrea
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3380955/
https://ncbi.nlm.nih.gov/pubmed/22737073
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1002774
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