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High ERK Protein Expression Levels Correlate with Shorter Survival in Triple-Negative Breast Cancer Patients

The mitogen-activated protein kinase (MAPK) signaling pathway is known to be activated in triple-negative breast cancer (TNBC). Extracellular signal–related kinase (ERK), a member of the MAPK pathway, promotes cell proliferation, angiogenesis, cell differentiation, and cell survival. To assess the p...

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Détails bibliographiques
Auteurs principaux: Bartholomeusz, Chandra, Gonzalez-Angulo, Ana M., Liu, Ping, Hayashi, Naoki, Lluch, Ana, Ferrer-Lozano, Jaime, Hortobágyi, Gabriel N.
Format: Artigo
Langue:Inglês
Publié: AlphaMed Press 2012
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3380875/
https://ncbi.nlm.nih.gov/pubmed/22584435
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1634/theoncologist.2011-0377
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