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Isolation of Monoclonal Antibodies with Predetermined Conformational Epitope Specificity
Existing technologies allow isolating antigen-specific monoclonal antibodies (mAbs) from B cells. We devised a direct approach to isolate mAbs with predetermined conformational epitope specificity, using epitope mimetics (mimotopes) that reflect the three-dimensional structure of given antigen subdo...
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Glavni autori: | , , , , , , , , , , , , , |
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Format: | Artigo |
Jezik: | Inglês |
Izdano: |
Public Library of Science
2012
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Teme: | |
Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3380854/ https://ncbi.nlm.nih.gov/pubmed/22737224 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0038943 |
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