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Liver hyperplasia after tamoxifen induction of Myc in a transgenic medaka model

Myc is a global transcriptional regulator and one of the most frequently overexpressed oncoproteins in human tumors. It is well established that activation of Myc leads to enhanced cell proliferation but can also lead to increased apoptosis. The use of animal models expressing deregulated levels of...

詳細記述

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書誌詳細
主要な著者: Menescal, Luciana A., Schmidt, Cornelia, Liedtke, Daniel, Schartl, Manfred
フォーマット: Artigo
言語:Inglês
出版事項: The Company of Biologists Limited 2012
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3380712/
https://ncbi.nlm.nih.gov/pubmed/22422827
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dmm.008730
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