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IL-33 family members and asthma – bridging innate and adaptive immune responses

The discovery of IL-33 as the ligand for the orphan Th2 associated receptor ST2 has uncovered a whole range of different avenues for this pathway. Although the extracellular functions of ST2 as a marker for Th2 cell and mast cell activity were well defined, the complexities of IL-33 regulation, nucl...

Ausführliche Beschreibung

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Bibliographische Detailangaben
1. Verfasser: Lloyd, Clare M
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2010
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3380518/
https://ncbi.nlm.nih.gov/pubmed/21071194
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.coi.2010.10.006
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