Evolution and classification of the CRISPR-Cas systems

The CRISPR–Cas (clustered regularly interspaced short palindromic repeats–CRISPR-associated proteins) modules are adaptive immunity systems that are present in many archaea and bacteria. These defence systems are encoded by operons that have an extraordinarily diverse architecture and a high rate of...

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Main Authors: S. Makarova, Kira, H. Haft, Daniel, Barrangou, Rodolphe, J. J. Brouns, Stan, Charpentier, Emmanuelle, Horvath, Philippe, Moineau, Sylvain, J. M. Mojica, Francisco, I. Wolf, Yuri, Yakunin, Alexander F., van der Oost, John, V. Koonin, Eugene
Format: Artigo
Jezik:Inglês
Izdano: 2011
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3380444/
https://ncbi.nlm.nih.gov/pubmed/21552286
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nrmicro2577
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