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Worsened Outcome from Middle Cerebral Artery Occlusion in Aged Rats Receiving 17β-Estradiol

Although estrogens are neuroprotective in young adult animal models of stroke, clinical trials demonstrate that estrogens increase the incidence and severity of stroke in aged women. We have previously shown that experimental stroke pathophysiology differs between young adult and aged rats. The aim...

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Autors principals: Leon, Rachel L., Li, Xinlan, Huber, Jason D., Rosen, Charles L.
Format: Artigo
Idioma:Inglês
Publicat: Endocrine Society 2012
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3380301/
https://ncbi.nlm.nih.gov/pubmed/22581460
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2011-1859
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