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Drugging Wnt signalling in cancer

Aberrant regulation of the Wnt signalling pathway has emerged as a prevalent theme in cancer biology. This chapter summarizes the research that provides a proof of concept for inhibiting Wnt signalling in cancer, the potential means by which this could be achieved, and some recent advances towards t...

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Detalhes bibliográficos
Autor principal: Polakis, Paul
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3380214/
https://ncbi.nlm.nih.gov/pubmed/22617421
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2012.126
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