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Suppressed hepcidin expression correlates with hypotransferrinemia in copper-deficient rat pups but not dams

Copper deficiency leads to anemia but the mechanism is unknown. Copper deficiency also leads to hypoferremia, which may limit erythropoiesis. The hypoferremia may be due to limited function of multicopper oxidases (MCO) hephaestin in enterocytes or GPI-ceruloplasmin in macrophages of liver and splee...

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Autors principals: Broderius, Margaret, Mostad, Elise, Prohaska, Joseph R.
Format: Artigo
Idioma:Inglês
Publicat: Springer-Verlag 2012
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3380187/
https://ncbi.nlm.nih.gov/pubmed/22457245
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12263-012-0293-7
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