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Suppressed hepcidin expression correlates with hypotransferrinemia in copper-deficient rat pups but not dams

Copper deficiency leads to anemia but the mechanism is unknown. Copper deficiency also leads to hypoferremia, which may limit erythropoiesis. The hypoferremia may be due to limited function of multicopper oxidases (MCO) hephaestin in enterocytes or GPI-ceruloplasmin in macrophages of liver and splee...

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Bibliografiske detaljer
Main Authors: Broderius, Margaret, Mostad, Elise, Prohaska, Joseph R.
Format: Artigo
Sprog:Inglês
Udgivet: Springer-Verlag 2012
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3380187/
https://ncbi.nlm.nih.gov/pubmed/22457245
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12263-012-0293-7
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