IL-17A Synergizes with IFN-γ to Upregulate iNOS and NO Production and Inhibit Chlamydial Growth

IFN-γ-mediated inducible nitric oxide synthase (iNOS) expression is critical for controlling chlamydial infection through microbicidal nitric oxide (NO) production. Interleukin-17A (IL-17A), as a new proinflammatory cytokine, has been shown to play a protective role in host defense against Chlamydia...

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Autors principals: Zhang, Yongci, Wang, Haiping, Ren, Jianyun, Tang, Xiaofei, Jing, Ye, Xing, Donghong, Zhao, Guosheng, Yao, Zhi, Yang, Xi, Bai, Hong
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2012
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3379979/
https://ncbi.nlm.nih.gov/pubmed/22745717
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0039214
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