Estimated clinical benefit of protecting neurogenesis in the developing brain during radiation therapy for pediatric medulloblastoma

We sought to assess the feasibility and estimate the benefit of sparing the neurogenic niches when irradiating the brain of pediatric patients with medulloblastoma (MB) based on clinical outcome data. Pediatric MB survivors experience a high risk of neurocognitive adverse effects, often attributed t...

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Detalhes bibliográficos
Main Authors: Blomstrand, Malin, Brodin, N. Patrik, Munck af Rosenschöld, Per, Vogelius, Ivan R., Sánchez Merino, Gaspar, Kiil-Berthlesen, Anne, Blomgren, Klas, Lannering, Birgitta, Bentzen, Søren M., Björk-Eriksson, Thomas
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2012
Assuntos:
Basic and Translational Investigations
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3379806/
https://ncbi.nlm.nih.gov/pubmed/22611031
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nos120
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