Importance of interaction between nerve growth factor and α9β1 integrin in glial tumor angiogenesis

NGF is a growth factor for which the role in the promotion of angiogenesis is still not completely understood. We found that NGF promotes the pathological neovascularization process in glioma through a direct interaction with α9β1 integrin, which is up-regulated on microvascular endothelial cells in...

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Bibliographic Details
Main Authors: Walsh, Erin M., Kim, Richard, Del Valle, Luis, Weaver, Michael, Sheffield, Joel, Lazarovici, Philip, Marcinkiewicz, Cezary
Format: Artigo
Language:Inglês
Published: Oxford University Press 2012
Subjects:
Basic and Translational Investigations
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3379805/
https://ncbi.nlm.nih.gov/pubmed/22611032
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nos119
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