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Pivotal role of mitochondrial Na(+)–Ca(2+) exchange in antigen receptor mediated Ca(2+) signalling in DT40 and A20 B lymphocytes

NON-TECHNICAL SUMMARY: Elevation of cytoplasmic Ca(2+) is one of the early responses of lymphocytes upon the antigen recognition by the surface receptor. We show here that the Ca(2+) response is maintained by Ca(2+) transfer from mitochondria to endoplasmic reticulum through mitochondrial Na(+)–Ca(2...

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Autores principales: Kim, Bongju, Takeuchi, Ayako, Koga, Orie, Hikida, Masaki, Matsuoka, Satoshi
Formato: Artigo
Lenguaje:Inglês
Publicado: Blackwell Science Inc 2012
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3379694/
https://ncbi.nlm.nih.gov/pubmed/22155933
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2011.222927
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