Conformational Analysis of a Genetically Encoded FRET Biosensor by SAXS

Genetically encoded FRET (Foerster resonance energy transfer) sensors are exciting tools in modern cell biology. Changes in the conformation of a sensor lead to an altered emission ratio and provide the means to determine both temporal and spatial changes in target molecules, as well as the activity...

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Bibliographic Details
Main Authors: Mertens, Haydyn D.T., Piljić, Alen, Schultz, Carsten, Svergun, Dmitri I.
Format: Artigo
Language:Inglês
Published: The Biophysical Society 2012
Subjects:
Protein
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3379623/
https://ncbi.nlm.nih.gov/pubmed/22735537
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2012.05.009
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