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Calcium Regulation of Myosin-I Tension Sensing

Myo1b is a myosin that is exquisitely sensitive to tension. Its actin-attachment lifetime increases > 50-fold when its working stroke is opposed by 1 pN of force. The long attachment lifetime of myo1b under load raises the question: how are actin attachments that last >50 s in the presence of...

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Détails bibliographiques
Auteurs principaux: Lewis, John H., Greenberg, Michael J., Laakso, Joseph M., Shuman, Henry, Ostap, E. Michael
Format: Artigo
Langue:Inglês
Publié: The Biophysical Society 2012
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3379621/
https://ncbi.nlm.nih.gov/pubmed/22735530
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2012.05.014
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