Contribution of the OBSCN Nonsynonymous Variants to Aspirin Exacerbated Respiratory Disease Susceptibility in Korean Population

Airway remodeling and exacerbated airway narrowing in asthma have been attributed to the regulation of intracellular Ca(2+) by sarcoplasmic reticulum (SR) of the airway smooth muscle cells. The protein encoded by obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF (OBSCN) is a crucial fac...

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Bibliographische Detailangaben
Hauptverfasser: Kim, Jeong-Hyun, Park, Byung-Lae, Pasaje, Charisse Flerida A., Kim, Yongha, Bae, Joon Seol, Park, Jong Sook, Uh, Soo-Taek, Kim, Yong-Hoon, Kim, Mi-Kyeong, Choi, Inseon S., Cho, Sang Heon, Choi, Byoung Whui, Koh, InSong, Park, Choon-Sik, Shin, Hyoung Doo
Format: Artigo
Sprache:Inglês
Veröffentlicht: Mary Ann Liebert, Inc. 2012
Schlagworte:
Original Research Articles
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3378958/
https://ncbi.nlm.nih.gov/pubmed/22251166
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/dna.2011.1436
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