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Evolution and function of CAG/polyglutamine repeats in protein–protein interaction networks
Expanded runs of consecutive trinucleotide CAG repeats encoding polyglutamine (polyQ) stretches are observed in the genes of a large number of patients with different genetic diseases such as Huntington's and several Ataxias. Protein aggregation, which is a key feature of most of these diseases...
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| 主要な著者: | , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Oxford University Press
2012
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3378862/ https://ncbi.nlm.nih.gov/pubmed/22287626 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gks011 |
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