MEF2C Ablation in Endothelial Cells Reduces Retinal Vessel Loss and Suppresses Pathologic Retinal Neovascularization in Oxygen-Induced Retinopathy

Ischemic retinopathies, including retinopathy of prematurity and diabetic retinopathy, are major causes of blindness. Both have two phases, vessel loss and consequent hypoxia-driven pathologic retinal neovascularization, yet relatively little is known about the transcription factors regulating these...

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Detalhes bibliográficos
Main Authors: Xu, Zhenhua, Gong, Junsong, Maiti, Debasish, Vong, Linh, Wu, Lijuan, Schwarz, John J., Duh, Elia J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Investigative Pathology 2012
Assuntos:
Regular Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3378855/
https://ncbi.nlm.nih.gov/pubmed/22521302
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2012.02.021
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