Loss of Msx2 Function Down-Regulates the FoxE3 Expression and Results in Anterior Segment Dysgenesis Resembling Peters Anomaly

Complex molecular interactions dictate the developmental steps that lead to a mature and functional cornea and lens. Peters anomaly is one subtype of anterior segment dysgenesis especially due to abnormal development of the cornea and lens. MSX2 was recently implicated as a potential gene that is cr...

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Bibliographic Details
Main Authors: Zhao, Jiangyue, Kawai, Kirio, Wang, Hongyan, Wu, Di, Wang, Mingwu, Yue, Zhicao, Zhang, Jinsong, Liu, Yi-Hsin
Format: Artigo
Language:Inglês
Published: American Society for Investigative Pathology 2012
Subjects:
Regular Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3378853/
https://ncbi.nlm.nih.gov/pubmed/22503753
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2012.02.017
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