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Spotiton: A prototype for an integrated inkjet dispense and vitrification system for cryo-TEM

Over the last three decades, Cryo-TEM has developed into a powerful technique for high-resolution imaging of biological macromolecules in their native vitrified state. However, the technique for vitrifying specimens onto EM grids is essentially unchanged – application of ~ 3 µL sample to a grid, fol...

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Bibliographic Details
Main Authors: Jain, Tilak, Sheehan, Patrick, Crum, John, Carragher, Bridget, Potter, Clinton S.
Format: Artigo
Language:Inglês
Published: 2012
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3378829/
https://ncbi.nlm.nih.gov/pubmed/22569522
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jsb.2012.04.020
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