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IL-25 induces type 2 cytokine production in a novel, steroid resistant IL-17RB(+) myeloid population that exacerbates asthmatic pathology
This study identifies the IL-25 receptor, IL-17RB, is an important mediator of both innate and adaptive pulmonary type 2 immune responses. Allergen exposure upregulated IL-25 and induced type 2 cytokine production in a novel granulocytic population, termed Type 2 Myeloid (T2M) cells. Il17rb(−/−) mic...
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2012
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3378776/ https://ncbi.nlm.nih.gov/pubmed/22543263 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nm.2735 |
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