Vascular Endothelial Dysfunction in β-Thalassemia Occurs Despite Increased eNOS Expression and Preserved Vascular Smooth Muscle Cell Reactivity to NO

AIMS: The hereditary β-thalassemia major condition requires regular lifelong blood transfusions. Transfusion-related iron overloading has been associated with the onset of cardiovascular complications, including cardiac dysfunction and vascular anomalies. By using an untransfused murine model of β-t...

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Main Authors: Stoyanova, Ekatherina, Trudel, Marie, Felfly, Hady, Lemsaddek, Wafaa, Garcia, Damien, Cloutier, Guy
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2012
Assuntos:
Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3378557/
https://ncbi.nlm.nih.gov/pubmed/22723848
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0038089
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