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Structural Constraints Identified with Covariation Analysis in Ribosomal RNA

Covariation analysis is used to identify those positions with similar patterns of sequence variation in an alignment of RNA sequences. These constraints on the evolution of two positions are usually associated with a base pair in a helix. While mutual information (MI) has been used to accurately pre...

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Detalhes bibliográficos
Main Authors: Shang, Lei, Xu, Weijia, Ozer, Stuart, Gutell, Robin R.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3378556/
https://ncbi.nlm.nih.gov/pubmed/22724009
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0039383
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