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Contribution of DEAF1 Structural Domains to the Interaction with the Breast Cancer Oncogene LMO4

The proteins LMO4 and DEAF1 contribute to the proliferation of mammary epithelial cells. During breast cancer LMO4 is upregulated, affecting its interaction with other protein partners. This may set cells on a path to tumour formation. LMO4 and DEAF1 interact, but it is unknown how they cooperate to...

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Détails bibliographiques
Auteurs principaux: Cubeddu, Liza, Joseph, Soumya, Richard, Derek J., Matthews, Jacqueline M.
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2012
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3378519/
https://ncbi.nlm.nih.gov/pubmed/22723967
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0039218
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