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Estimation of heritability from limited family data using genome-wide identity-by-descent sharing

BACKGROUND: In classical pedigree-based analysis, additive genetic variance is estimated from between-family variation, which requires the existence of larger phenotyped and pedigreed populations involving numerous families (parents). However, estimation is often complicated by confounding of geneti...

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Detalhes bibliográficos
Main Authors: Ødegård, Jørgen, Meuwissen, Theo HE
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3378432/
https://ncbi.nlm.nih.gov/pubmed/22568689
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1297-9686-44-16
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