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Regulation of presynaptic strength by controlling Ca(2+) channel mobility: effects of cholesterol depletion on release at the cone ribbon synapse

Synaptic communication requires proper coupling between voltage-gated Ca(2+) (Ca(V)) channels and synaptic vesicles. In photoreceptors, L-type Ca(V) channels are clustered close to synaptic ribbon release sites. Although clustered, Ca(V) channels move continuously within a confined domain slightly l...

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Main Authors: Mercer, Aaron J., Szalewski, Robert J., Jackman, Skyler L., Van Hook, Matthew J., Thoreson, Wallace B.
Format: Artigo
Jezik:Inglês
Izdano: American Physiological Society 2012
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3378415/
https://ncbi.nlm.nih.gov/pubmed/22442573
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/jn.00779.2011
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