Hypoxia Inducible Factor-1 (HIF-1) Independent Microvascular Angiogenesis in the Aged Rat Brain

Angiogenesis is a critical component of mammalian brain adaptation to prolonged hypoxia. Hypoxia-induced angiogenesis is mediated by hypoxia inducible factor-1 (HIF-1) dependent transcriptional activation of growth factors, such as vascular endothelial growth factor (VEGF). Microvascular angiogenesi...

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Main Authors: Ndubuizu, Obinna I., Tsipis, Constantinos P., Li, Ang, LaManna, Joseph C.
Formato: Artigo
Idioma:Inglês
Publicado: 2010
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3378376/
https://ncbi.nlm.nih.gov/pubmed/20875806
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.brainres.2010.09.064
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