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Wnt signaling strength regulates normal hematopoiesis and its deregulation is involved in leukemia development
A strict balance between self-renewal and differentiation of hematopoietic stem cells (HSCs) is required in order to maintain homeostasis, as well as to efficiently respond to injury and infections. Numbers and fate decisions made by progenitors derived from HSC must also be carefully regulated to s...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3378318/ https://ncbi.nlm.nih.gov/pubmed/22173215 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/leu.2011.387 |
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