TGF-β and Smad3 modulate PI3K/Akt signaling pathway in vascular smooth muscle cells

Transforming growth factor-β (TGF-β) is upregulated at the time of arterial injury; however, the mechanism through which TGF-β enhances the development of intimal hyperplasia is not clear. Recent studies from our laboratory suggest that in the presence of elevated levels of Smad3, TGF-β stimulates s...

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Main Authors: Suwanabol, Pasithorn A., Seedial, Stephen M., Zhang, Fan, Shi, Xudong, Si, Yi, Liu, Bo, Kent, K. Craig
Format: Artigo
Sprog:Inglês
Udgivet: American Physiological Society 2012
Fag:
Vascular Biology and Microcirculation
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3378292/
https://ncbi.nlm.nih.gov/pubmed/22447946
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00966.2011
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