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Development and evaluation of new cyclooctynes for cell surface glycan imaging in cancer cells

Two reagents have been synthesized for selective labeling of cell surface azidoglycans, an unusually stable version of a dibenzocyclooctyne (TMDIBO) and a third-generation difluorinated cyclooctyne (DIFO3). Both syntheses are efficient with minimal purification, and the dibenzocyclooctyne is stable...

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Detalhes bibliográficos
Main Authors: Stöckmann, Henning, Neves, André A., Stairs, Shaun, Ireland-Zecchini, Heather, Brindle, Kevin M., Leeper, Finian J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3378185/
https://ncbi.nlm.nih.gov/pubmed/22724056
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/C0SC00631A
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