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Proteomic profiling of the effect of metabolic acidosis on the apical membrane of the proximal convoluted tubule

The physiological response to the onset of metabolic acidosis requires pronounced changes in renal gene expression. Adaptations within the proximal convoluted tubule support the increased extraction of plasma glutamine and the increased synthesis and transport of glucose and of NH(4)(+) and HCO(3)(−...

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Bibliografiske detaljer
Main Authors: Walmsley, Scott J., Freund, Dana M., Curthoys, Norman P.
Format: Artigo
Sprog:Inglês
Udgivet: American Physiological Society 2012
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3378174/
https://ncbi.nlm.nih.gov/pubmed/22357915
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00390.2011
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