Feedback via Ca(2+)-Activated Ion Channels Modulates Endothelin 1 Signaling in Retinal Arteriolar Smooth Muscle

PURPOSE. To investigate the role of feedback by Ca(2+)-sensitive plasma-membrane ion channels in endothelin 1 (Et1) signaling in vitro and in vivo. METHODS. Et1 responses were imaged from Fluo-4–loaded smooth muscle in isolated segments of rat retinal arteriole using two-dimensional (2-D) confocal l...

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Main Authors: Stewart, Michael, Needham, Maurice, Bankhead, Peter, Gardiner, Tom A, Scholfield, C. Norman, Curtis, Tim M, McGeown, J. Graham
Format: Artigo
Language:Inglês
Published: The Association for Research in Vision and Ophthalmology 2012
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Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3378088/
https://ncbi.nlm.nih.gov/pubmed/22427579
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.11-9192
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