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Endothelin 1 Stimulates Ca(2+)-Sparks and Oscillations in Retinal Arteriolar Myocytes via IP(3)R and RyR-Dependent Ca(2+) Release

PURPOSE. To investigate endothelin 1 (Et1)–dependent Ca(2+)-signaling at the cellular and subcellular levels in retinal arteriolar myocytes. METHODS. Et1 responses were imaged from Fluo-4–loaded smooth muscle in isolated segments of rat retinal arteriole using confocal laser microscopy. RESULTS. Bas...

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Detalhes bibliográficos
Main Authors: Tumelty, James, Hinds, Kevin, Bankhead, Peter, McGeown, Neil J., Scholfield, C. Norman, Curtis, Tim M., McGeown, J. Graham
Formato: Artigo
Idioma:Inglês
Publicado em: Association for Research in Vision and Ophthalmology, Inc. 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3109063/
https://ncbi.nlm.nih.gov/pubmed/21372022
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.10-6029
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