SIX2 AND CITED1, MARKERS OF NEPHRONIC PROGENITOR SELF-RENEWAL, REMAIN ACTIVE IN PRIMITIVE ELEMENTS OF WILMS TUMOR

PURPOSE: SIX2 and CITED1 are transcriptional regulators that specify self-renewing nephronic progenitor cells of the embryonic kidney. We hypothesized that SIX2, which promotes and maintains this stem cell population, and CITED1 remain active in Wilms Tumor (WT). METHODS: To evaluate expression doma...

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Hauptverfasser: Murphy, Andrew J., Pierce, Janene, de Caestecker, Christian, Taylor, Chase, Anderson, James R., Perantoni, Alan O., de Caestecker, Mark P., Lovvorn, Harold N.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2012
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3377935/
https://ncbi.nlm.nih.gov/pubmed/22703800
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jpedsurg.2012.03.034
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