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Pain Sensitivity and Opioid Analgesia: A Pharmacogenomic Twin Study

Opioids are the cornerstone medication for the management of moderate to severe pain. Unfortunately, vast inter-individual differences in dose requirements complicate their effective and safe clinical use. Mechanisms underlying such differences are incompletely understood, are likely multifactorial,...

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Main Authors: Angst, Martin S., Phillips, Nicholas G., Drover, David R., Tingle, Martha, Ray, Amrita, Swan, Gary E., Lazzeroni, Laura C., Clark, J. David
格式: Artigo
語言:Inglês
出版: 2012
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3377769/
https://ncbi.nlm.nih.gov/pubmed/22444188
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.pain.2012.02.022
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