A Novel Pathway Regulates Thyroid Hormone Availability in Rat and Human Hypothalamic Neurosecretory Neurons

Hypothalamic neurosecretory systems are fundamental regulatory circuits influenced by thyroid hormone. Monocarboxylate-transporter-8 (MCT8)-mediated uptake of thyroid hormone followed by type 3 deiodinase (D3)-catalyzed inactivation represent limiting regulatory factors of neuronal T3 availability....

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Détails bibliographiques
Auteurs principaux: Kalló, Imre, Mohácsik, Petra, Vida, Barbara, Zeöld, Anikó, Bardóczi, Zsuzsanna, Zavacki, Ann Marie, Farkas, Erzsébet, Kádár, Andrea, Hrabovszky, Erik, Arrojo e Drigo, Rafael, Dong, Liping, Barna, László, Palkovits, Miklós, Borsay, Beáta A., Herczeg, László, Lechan, Ronald M., Bianco, Antonio C., Liposits, Zsolt, Fekete, Csaba, Gereben, Balázs
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2012
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3377717/
https://ncbi.nlm.nih.gov/pubmed/22719854
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0037860
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