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Evaluation of Poly-Mechanistic Antiangiogenic Combinations to Enhance Cytotoxic Therapy Response in Pancreatic Cancer

Gemcitabine (Gem) has limited clinical benefits in pancreatic ductal adenocarcinoma (PDAC). The present study investigated combinations of gemcitabine with antiangiogenic agents of various mechanisms for PDAC, including bevacizumab (Bev), sunitinib (Su) and EMAP II. Cell proliferation and protein ex...

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Détails bibliographiques
Auteurs principaux: Awasthi, Niranjan, Zhang, Changhua, Ruan, Winston, Schwarz, Margaret A., Schwarz, Roderich E.
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2012
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3377661/
https://ncbi.nlm.nih.gov/pubmed/22723862
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0038477
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