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Effects of Aging on Endotoxin Tolerance Induced by Lipopolysaccharides Derived from Porphyromonas gingivalis and Escherichia coli

BACKGROUND: Periodontitis is a bacterially induced chronic inflammatory disease. Exposure of the host to periodontal pathogens and their virulence factors induces a state of hyporesponsiveness to subsequent stimulations, termed endotoxin tolerance. Aging has a profound effect on immune response to b...

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Bibliografiske detaljer
Main Authors: Sun, Ying, Li, Hui, Yang, Mi-Fang, Shu, Wei, Sun, Meng-Jun, Xu, Yan
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2012
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3377652/
https://ncbi.nlm.nih.gov/pubmed/22723968
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0039224
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