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Functional Phenotypic Rescue of Caenorhabditis elegans Neuroligin-Deficient Mutants by the Human and Rat NLGN1 Genes

Neuroligins are cell adhesion proteins that interact with neurexins at the synapse. This interaction may contribute to differentiation, plasticity and specificity of synapses. In humans, single mutations in neuroligin encoding genes lead to autism spectrum disorder and/or mental retardation. Caenorh...

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Detalhes bibliográficos
Main Authors: Calahorro, Fernando, Ruiz-Rubio, Manuel
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3377638/
https://ncbi.nlm.nih.gov/pubmed/22723984
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0039277
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