miR-337-3p and Its Targets STAT3 and RAP1A Modulate Taxane Sensitivity in Non-Small Cell Lung Cancers

NSCLC (non-small cell lung cancer) often exhibits resistance to paclitaxel treatment. Identifying the elements regulating paclitaxel response will advance efforts to overcome such resistance in NSCLC therapy. Using in vitro approaches, we demonstrated that over-expression of the microRNA miR-337-3p...

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Hlavní autoři: Du, Liqin, Subauste, Maria C., DeSevo, Christopher, Zhao, Zhenze, Baker, Michael, Borkowski, Robert, Schageman, Jeoffrey J., Greer, Rachel, Yang, Chin-Rang, Suraokar, Milind, Wistuba, Ignacio I., Gazdar, Adi F., Minna, John D., Pertsemlidis, Alexander
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2012
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3377607/
https://ncbi.nlm.nih.gov/pubmed/22723956
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0039167
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