Melatonin synthesis in retina: cAMP-dependent transcriptional regulation of chicken arylalkylamine N-acetyltransferase (Aanat) by a CRE-like sequence (CLS) and a TTATT repeat motif in the proximal promoter

Arylalkylamine N-acetyltransferase (AANAT) is the key regulatory enzyme controlling the daily rhythm of melatonin biosynthesis. In chicken retinal photoreceptor cells, Aanat transcription and AANAT activity are regulated in part by cAMP-dependent mechanisms. The purpose of this study was to identify...

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Detalhes bibliográficos
Main Authors: Haque, Rashidul, Chong, Nelson W., Ali, Fatima, Chaurasia, Shyam S., Sengupta, Trisha, Chun, Eugene, Howell, Jennifer C., Klein, David C., Iuvone, P. Michael
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3377444/
https://ncbi.nlm.nih.gov/pubmed/21790603
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1471-4159.2011.07397.x
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