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Profile of peginesatide and its potential for the treatment of anemia in adults with chronic kidney disease who are on dialysis
Peginesatide is a synthetic, dimeric peptide that is covalently linked to polyethylene glycol (PEG). The amino acid sequence of peginesatide is unrelated to that of erythropoietin (EPO) and is not immunologically cross-reactive with EPO. Peginesatide binds to and activates the human EPO receptor, st...
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Dove Medical Press
2012
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| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3377433/ https://ncbi.nlm.nih.gov/pubmed/22719216 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/JBM.S23270 |
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