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How Hibernation Factors RMF, HPF, and YfiA Turn Off Protein Synthesis

Eubacteria inactivate their ribosomes as 100S dimers or 70S monomers upon entry into stationary phase. In Escherichia coli, 100S dimer formation is mediated by ribosome modulation factor (RMF) and hibernation promoting factor (HPF), or alternatively, the YfiA protein inactivates ribosomes as 70S mon...

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Bibliographic Details
Main Authors: Polikanov, Yury S., Blaha, Gregor M., Steitz, Thomas A.
Format: Artigo
Language:Inglês
Published: 2012
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3377384/
https://ncbi.nlm.nih.gov/pubmed/22605777
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1218538
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