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Progress Towards Simple and Direct Detection of Adenylosuccinate Lyase Deficiency in Human Urine
A rhodamine based boronic acid linearly responds to increasing 5-aminoimidazole-4-carboxamide riboside (AICAr) concentrations in human urine. This method is thus an advance in detecting adenylosuccinate lyase (ADSL) deficiency as AICAr is a model riboside for the ADSL substrates succinyladenosine (S...
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| Main Authors: | , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2011
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3377351/ https://ncbi.nlm.nih.gov/pubmed/22719107 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1071/CH11328 |
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