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Progress Towards Simple and Direct Detection of Adenylosuccinate Lyase Deficiency in Human Urine

A rhodamine based boronic acid linearly responds to increasing 5-aminoimidazole-4-carboxamide riboside (AICAr) concentrations in human urine. This method is thus an advance in detecting adenylosuccinate lyase (ADSL) deficiency as AICAr is a model riboside for the ADSL substrates succinyladenosine (S...

詳細記述

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書誌詳細
主要な著者: Lim, Soojin, Lowry, Mark, Strongin, Robert M.
フォーマット: Artigo
言語:Inglês
出版事項: 2011
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3377351/
https://ncbi.nlm.nih.gov/pubmed/22719107
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1071/CH11328
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