Down-regulation of BRCA1 expression by miR-146a and miR-146b-5p in triple negative sporadic breast cancers

Germ-line mutations in the BRCA1 gene strongly predispose women to breast cancer (lifetime risk up to 80%). Furthermore, the BRCA1 protein is absent or present at very low levels in about one third of sporadic breast cancers. However, the mechanisms underlying BRCA1 somatic inactivation appear multi...

Popoln opis

Shranjeno v:
Bibliografske podrobnosti
Main Authors: Garcia, Amandine I, Buisson, Monique, Bertrand, Pascale, Rimokh, Ruth, Rouleau, Etienne, Lopez, Bernard S, Lidereau, Rosette, Mikaélian, Ivan, Mazoyer, Sylvie
Format: Artigo
Jezik:Inglês
Izdano: WILEY-VCH Verlag 2011
Teme:
Research Articles
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3377076/
https://ncbi.nlm.nih.gov/pubmed/21472990
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/emmm.201100136
Oznake: Označite
Brez oznak, prvi označite!

Podobne knjige/članki