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Allelic and genotype frequencies of catechol-O-methyltransferase (Val158Met) and CYP2D6*10 (Pro34Ser) single nucleotide polymorphisms in the Philippines

A hospital-based cross-sectional study was conducted to determine the allelic and genotype frequencies in the genes encoding for catechol-O-methyltransferase and CYP2D6*10 among healthy volunteers and patients clinically diagnosed with cancer pain. PCR-RFLP was used to identify COMT and CYP2D6*10 ge...

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Detalhes bibliográficos
Main Authors: Baclig, Michael O, Predicala, Rey Z, Mapua, Cynthia A, Lozano-Kühne, Jingky P, Daroy, Maria Luisa G, Natividad, Filipinas F, Javier, Francis O
Formato: Artigo
Idioma:Inglês
Publicado em: e-Century Publishing Corporation 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3376921/
https://ncbi.nlm.nih.gov/pubmed/22724048
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