The Human Phospholamban Arg14-Deletion Mutant Localizes to Plasma Membrane and Interacts with the Na/K-ATPase

Depressed Ca-handling in cardiomyocytes is frequently attributed to impaired sarcoplasmic reticulum (SR) function in human and experimental heart failure. Phospholamban (PLN) is a key regulator of SR and cardiac function, and PLN mutations in humans have been associated with dilated cardiomyopathy (...

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Bibliografiske detaljer
Main Authors: Haghighi, Kobra, Pritchard, Tracy, Bossuyt, Julie, Waggoner, Jason R., Yuan, Qunying, Fan, Guo-Chang, Osinska, Hanna, Anjak, Ahmad, Rubinstein, Jack, Robbins, Jeffrey, Bers, Donald M., Kranias, Evangelia G.
Format: Artigo
Sprog:Inglês
Udgivet: 2011
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3376549/
https://ncbi.nlm.nih.gov/pubmed/22155237
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.yjmcc.2011.11.012
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