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The Human Phospholamban Arg14-Deletion Mutant Localizes to Plasma Membrane and Interacts with the Na/K-ATPase
Depressed Ca-handling in cardiomyocytes is frequently attributed to impaired sarcoplasmic reticulum (SR) function in human and experimental heart failure. Phospholamban (PLN) is a key regulator of SR and cardiac function, and PLN mutations in humans have been associated with dilated cardiomyopathy (...
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Main Authors: | , , , , , , , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2011
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3376549/ https://ncbi.nlm.nih.gov/pubmed/22155237 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.yjmcc.2011.11.012 |
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