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Immune stress in late pregnant rats decreases length of gestation and fecundity, and alters later cognitive and affective behaviour of surviving pre-adolescent offspring

Immune challenge during pregnancy is associated with preterm birth and poor perinatal development. The mechanisms of these effects are not known. 5α-Pregnan-3α-ol-20-one (3α,5α-THP), the neuroactive metabolite of progesterone, is critical for neurodevelopment and stress responses, and can influence...

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Bibliografiska uppgifter
Huvudupphovsmän: PARIS, JASON J., BRUNTON, PAULA J., RUSSELL, JOHN A., FRYE, CHERYL A.
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2011
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Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3376536/
https://ncbi.nlm.nih.gov/pubmed/21995525
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3109/10253890.2011.628719
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