Influence of SLCO1B3 haplotype-tag SNPs on docetaxel disposition in Chinese nasopharyngeal cancer patients

AIMS: To completely screen the SLCO1B3 gene in three distinct healthy Asian populations (Chinese, Malay and Indian, n = 168) and investigate the influence of haplotype-tag SNPs (htSNPs) on docetaxel disposition in 50 nasopharyngeal carcinoma patients. METHODS: Genomic DNA of individuals was screened...

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Autores principales: Chew, Sin Chi, Sandanaraj, Edwin, Singh, Onkar, Chen, Xiangai, Tan, Eng Huat, Lim, Wan Teck, Lee, Edmund J D, Chowbay, Balram
Formato: Artigo
Lenguaje:Inglês
Publicado: Blackwell Science Inc 2012
Materias:
Pharmacogenetics
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3376437/
https://ncbi.nlm.nih.gov/pubmed/21995462
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2125.2011.04123.x
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