Novel Use of a Lipid-Lowering Fibrate Medication to Prevent Nicotine Reward and Relapse: Preclinical Findings

Experimental drugs that activate α-type peroxisome proliferator-activated receptors (PPARα) have recently been shown to reduce the rewarding effects of nicotine in animals, but these drugs have not been approved for human use. The fibrates are a class of PPARα-activating medications that are widely...

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Detalhes bibliográficos
Main Authors: Panlilio, Leigh V, Justinova, Zuzana, Mascia, Paola, Pistis, Marco, Luchicchi, Antonio, Lecca, Salvatore, Barnes, Chanel, Redhi, Godfrey H, Adair, Jordan, Heishman, Stephen J, Yasar, Sevil, Aliczki, Mano, Haller, Jozsef, Goldberg, Steven R
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2012
Assuntos:
Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3376316/
https://ncbi.nlm.nih.gov/pubmed/22453137
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/npp.2012.31
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